Products

DESCRIPTION

Basic Info

Model NO.	BS62258
Supply Type	OBM(Original Brand Manufacturing)
Usage Mode	For oral administration
Suitable for	Elderly, Adult
Type	Biological Diagnostic Reagents
Application	for Diagnosis, for Therapy, for Prevention
Form	Liquid
Specification	100ug/1mg
Trademark	Bioworld
Origin	China
Production Capacity	3000 Vials

Product Description

Catalog No.	AP0060
Product Name	β-Actin (I102) polyclonal antibody
Applications	WB
Alternative Name	Actin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed; ACTB; Actin-β; Beta actin;
Swiss-Prot	N A
Host	Rabbit
Reactivity	Human,Mouse,Rat
Application_all	WB:1:5000~1:20000
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity	β-actin (I102) polyclonal antibody detects endogenous levels of β-actin protein.
BiowMW	~ 42 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant full length Human β-Actin.

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  Western blot (WB) analysis of β-Actin (I102) pAb at 1:5000/1:10000/1:20000 dilution

Background

All eukaryotic cells express actin, which often constitutes asmuch as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of actin are present in mammalian tissues and fall into three classes. -actin expression is limited to various types of muscle, whereas - and -actin are the principle constituents of filaments in other tissues.Members of the small GTPase family regulate the organization of the actin cytoskeleton. Rho controls the assembly of ctin stress fibers and focal adhesion, Rac regulates ctin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.