Products

DESCRIPTION

Basic Info

Model NO.	62304-98-7
CAS No.	67727-97-3
Mf	C129h215n33o55
MW	3108.32
Einecs	1592732-453-0
Transport Package	Discreet Package
Specification	1kg in one bag, 20kgs in one drum
Trademark	INNO
Origin	China
Production Capacity	500kg/Week

Product Description

Research Chemical High Purity 99.0%Min. Thymosin Alpha 1 Thymalfasin 62304-98-7 Peptide Raw Powder with The Best Price Product name: Thymosin Alpha 1 ThymalfasinCas No.: 62304-98-7Purity: 99.0%min.Appearance: white powderAppearance: White Crystalline Lyophilized PowderPackage: 1mg,2mg,5mg.10mgShelf Life :24MonthsStorage:Refrigeration keep dry and away from light.Sequence:Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH Introduction:Thymosin alpha 1 (Tα1), a 28-amino acid peptide, was first described and characterized from calf thymuses in 1977. This peptide can enhance T-cell, dendritic cell (DC) and antibody responses, modulate cytokines and chemokines production and block steroid-induced apoptosis of thymocytes. Due to its pleiotropic biological activities, Tα1 has gained increasing interest in recent years and has been used for the treatment of various diseases in clinic. Accordingly, there is an increasing need for the production of this peptide. So far, Tα1 used in clinic is synthesized using solid phase peptide synthesis. Here, we summarize the genetic engineering methods to produce Tα1 using prokaryotic or eukaryotic expression systems. The effectiveness of these biological products in increasing the secretion of cytokines and in promoting lymphocyte proliferation were investigated in vitro studies. This opens the possibility for biotechnological production of Tα1 for the research and clinical applications.Research highlightsThymosin alpha 1 (Tα1) has a lot of biological activities. Tα1 has a broad spectrum of applications in clinic. Genetic engineering expression of Tα1 has attracted more attention recently. Tα1 products obtained by genetic engineering may be applied in clinic in the future.